POSTDOC POSITION in microbiome-targeted biotherapeutics for oral cancer treatment

A Postdoctoral Scholar position is available immediately in the laboratory of Dr. Maria Marco, The University of California, Davis. The Marco lab investigates interactions between commensal and ingested bacteria in gastrointestinal tract and the impacts of beneficial microbes individually and collectively on health. This position is focused on elucidating the molecular mechanisms via which a bacteriocin exerts antimicrobial and host-modulatory effects in the oral cavity to reverse oral dysbiosis and protect against tumorigenesis. Oral dysbiosis can pre-dispose an individual to oral disease, including cancer, by enriching for bacterial pathogens that promote carcinogenesis, secrete carcinogenic compounds, and promote chronic inflammation. Thus, reversing oral dysbiosis is a promising approach for protecting against tumorigenesis. Bacteriocins are secreted peptides made by members of food and mammalian microbiomes and have significant therapeutic potential to restore oral microbiome diversity, suppress inflammation, and stimulate anti-tumor cellular responses. Qualified candidates should have a strong background in two or more of the following: microbiological, molecular biology, and microbiome bioinformatics methods. The successful candidate should have a PhD degree by the appointment date, no more than three years post-degree research experience, and be proficient in written and oral English. The position is available immediately for two years with the possibility of renewal contingent on performance. The UC Davis Office of Graduate Studies is the administrative home for postdoctoral scholars. Relevant information resources, benefits and orientations can be found at https://grad.ucdavis.edu/resources-uc-davis-postdoctoral-scholars. To apply, send a cover letter citing the title of this announcement, Curriculum Vitae, and contact information for 2 to 3 references to Professor Marco at mmarco@ucdavis.edu.

For more information, see the attached full position description.